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Leptin is a peptide that is strongly correlated with adiposity and is a potential determinant of obesity and its complications.
Since first reported less than a decade ago (1), leptin has been a topic of considerable study. The variation in serum or plasma leptin concentrations has been described according to sex, age, measu...
Although it is known that plasma leptin concentrations correlate with the amount of adipose tissue in the body, little information is available on the long-term effects on leptin concentrations of ...
Plasma leptin in humans is subject to both longand short-term regulation; it correlates with indexes of body fat that can only change slowly. However, short-term fasting causes large and rapid decr...
During the past 2 y the leptin field has continued to expand rapidly (from 600 to >2000 citations currently in the MEDLINE database), extending leptin biology into areas well beyond feeding behavior a...
Little is known about the effects of physical training on plasma leptin concentrations in children.
Leptin is known to be cleared by the kidney, a tissue with substantial leptin receptor mRNA expression; however, lung, liver, and muscle tissues also express leptin receptor messenger RNA and it is...
Background: Leptin is secreted by adipose tissue and decreases appetite. However, the role of leptin in the pathogenesis of hemodialysis (HD)-related malnutrition has not been fully evaluated.
Background:Liver cirrhosis is associated with reduced energy intake and increased resting energy expenditure. Objective:We aimed to investigate the possible role of glucose, insulin, leptin, and ghrel...
Background:Because serum concentrations of leptin, a hormone produced by adipocytes, can be relatively reliably and inexpensively measured, it may be considered complementary to, or even a substitute ...
Leptin and its soluble receptor (sOB-R) are important to regulation of body composition but there are no data on the developmental variations in these plasma variables and their relationship with body...
Increasing evidence suggests that falling leptin concentrations observed during fasting act as a peripheral signal of starvation, which serves to conserve energy in the face of limited reserves. An ex...
Pulmonary tuberculosis is the classic cause of “consumption,” but the pathogenesis of such wasting is largely unknown. Animal studies in other conditions suggest that leptin may be a mediator between ...
Background: Formula feeding or overweight in infancy may increase the later risk of obesity, but the mechanisms involved are uncertain. Because obesity is associated with high leptin concentratio...

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