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Critically ill patients are characterized by a hypermetabolic state, a catabolic response, higher nutritional needs, and a decreased capacity for utilization of parenteral substrate.
Results of leptin administration in mice, rats, and humans provide a rationale for therapeutic augmentation of circulating leptin (OB protein) concentrations in obese humans; this may reduce food i...
Recent reports have identified a lower resting metabolic rate in African Americans than in whites, but most studies included only females and used short-term measurements with ventilated-hood syste...
In their study, Marshall et al (1) found a significant relation between serum LDL cholesterol and saturated fat intake when random-effects models for longitudinal data were used. The model paramete...
Pulmonary tuberculosis is the classic cause of “consumption,” but the pathogenesis of such wasting is largely unknown. Animal studies in other conditions suggest that leptin may be a mediator between ...
Obesity represents a major threat to health and quality of life. Although obesity has strong genetic determinants, it is generally accepted that it results from an imbalance between food intake and da...
This study was performed retrospectively to investigate the relation between skeletal muscle enzymes and 24-h energy metabolism in obese persons before and after weight loss.
Background: Dietary fat composition is thought to affect body weight regulation independent of the amount of fat ingested.Objective: We analyzed the feeding behavior, body weight gain, body ...
Background: An adaptive decrease in energy expenditure (EE) in response to 6 mo of severely restricted energy intake was shown in a classic semistarvation study—the Minnesota experiment. Objective:...

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