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The antifertility effect of triptolide and other related compounds, isolated from Tripterygium wilfordii, has been demonstrated in male rats. The exact sites and mechanism of action of triptolide ...
Long-term effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats
spermatogenesis epididymal sperm function fertility male rats
2008/12/25
Prior studies had suggested that triptolide, a diterpene triepoxide isolated from a Chinese medicinal plant, might be an attractive candidate as a post-testicular male contraceptive agent. Despite the...
Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure
Posttesticular antifertility action triptolide male rat sperm ultrastructure
2008/12/25
A variety of active diterpene epoxides, including the triptolide (isolated from Tripterygium wilfordii) have been reported to cause infertility in male rats. Previously, we showed that oral admini...