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Involvement of endothelial nitric oxide synthase in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbit
Hypercholesterolemia cavernous smooth muscle
2009/2/18
The present study was designed to evaluate whether functional impairment and/or protein expression of constitutive nitric oxide synthase (cNOS; endothelial NOS [eNOS] and neuronal NOS[nNOS]) was i...
Androgens modulate the alpha-adrenergic responsiveness of vascular smooth muscle in the corpus cavernosum
Penile erection testosterone adrenergic prazosin
2009/2/17
Rat penile erection is an androgen-dependent process with castration leading to a loss of potency. The present study was designed to determine if one of the mechanisms by which androgens maintain th...
Expression of inducible nitric oxide synthase in smooth muscle cells from rat penile corpora cavernosa
inducible nitric oxide synthase smooth muscle cells rat penile corpora cavernosa
2009/2/13
Nitric oxide (NO), the main mediator of penile erection, is assumed to be synthesized in the penis by the neuronal constitutive nitric oxide synthase (nNOS). However, nNOS has not been identifie...
The effect of vasoactive intestinal polypeptide（VIP）on rabbit cavernosal smooth muscle contractility
Vasoactive intestinal polypeptide calcium cyclic GMP rabbit corpus cavemosum
2009/2/12
Vasoactive intestinal polypeptide (VIP) has emerged as a possible candidate for a nonadrenergic, noncholinergic inhibitory neurotransmitter in penile erection. In this study, the effect of VIP and i...
Appearance of alpha-smooth muscle actin in peritubular cells of monkey testes is induced by androgens, modulated by follicle-stimulating hormone, and maintained after hormonal withdrawal
alpha-smooth muscle actin peritubular cells androgens follicle-stimulating hormone
2009/2/12
This study analyzed the hormonal requirements necessary for the development of primate testicular peritubular cells. Alpha-smooth muscle actin, as a specific differentiation marker for peritubular c...
Characterization of K currents in cultured human corporal smooth muscle cells
Human corpus cavernosum vascular smooth muscle K channels patch clamp studies electrophysiology
2009/2/12
In order to gain more mechanistic insight into the regulation of corporal smooth muscle tone, we conducted electrophysiological studies on homogeneous explant cell cultures of human corpus caverno...
Smooth Muscle Cell Behavior in the Ventral Prostate of Castrated Rats
Androgen castration SEM stereological analysis smoothelin smooth muscle myosin
2008/12/22
Smooth muscle cells (SMC) play roles in prostatic development and function. The cells also respond to tissue injury and hormonal variations, alternating between a fully differentiated and contractil...
Corpus Cavernosum Smooth Muscle Physiology: A Role for Sex Hormones?
Corpus Cavernosum Smooth Muscle Physiology Role Sex Hormones
2008/12/19
The penis contains 3 long cylindrical tubes of tissue: the corpus spongiosum and dorsally a pair of corpus cavernosum (CC) (Figure 1A). The CC is contained within a tough outer covering known as t...