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黄芪甲苷对病毒性心肌炎小鼠TLR4、NF-κB及TNF-α表达的影响
心肌炎 NF-κB 肿瘤坏死因子α 黄芪甲苷
2012/7/12
探讨黄芪甲苷对病毒性心肌炎小鼠Toll样受体4(TLR4)mRNA、核因子-κB(NF-κB)mRNA表达及血清肿瘤坏死因子(TNF-α)的影响。方法 将80只雄性BALB/c小鼠随机分为柯萨奇病毒感染组(感染组,30只)、黄芪甲苷治疗组(治疗组，30只)和正常对照组(对照组,20只)。感染组和治疗组小鼠腹腔注射柯萨奇病毒B3(CVB3)，建立病毒性心肌炎模型。治疗组于注射病毒后30 min开始灌...
Lack of association between TLR4 polymorphism and severe gram-negative bacterial infection in neonates
Neonate TLR4 gram-negative infections
2009/7/6
Aim: Gram-negative microorganisms are responsible for a significant percentage of systemic bacterial infections in neonates, which tend to progress to sepsis. Toll-like receptor 4 (TLR4), one of the ...