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上调miR-181a抑制香烟提取物诱导的支气管上皮细胞致炎因子生成与collagen IV、fibronectin和α-SMA表达
微小RNA-181a 慢性阻塞性肺疾病 气道炎症 气道重塑 NF-κB/TGF-β1/Smad3信号通路
2020/9/11
探讨微小RNA-181a（miR-181a）对香烟提取物（cigarette smoke extract，CSE）诱导的人支气管上皮细胞（human bronchial epithelial cells， HBECs）致炎因子生成与IV型胶原蛋白（collagen IV）、纤连蛋白（fibronectin）和α-平滑肌肌动蛋白（α-SMA）表达的影响，并分析其可能的机制。方法：RT-qPCR检测C...
Clinical and experimental studies on fibronectin in bronchial asthma
bronchial asthma eosinophil adherence eosinophil chemotaxis eosinophils fibronectin
2010/11/24
Background: Clinical and experimental studies were performed to investigate the kinetics of fibronectin (FN) and its clinical significance in bronchial asthma.
Methods: Measurements of plasma fibrone...