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Combination of Angiotensin Converting Enzyme Insertion/Deletion (I/D) (rs4646994) and VEGF Polymorphism (+405G/C; rs2010963) Synergistically Associated With the Development, of Albuminuria in Iranian Patients With Type 2 Diabetes
Vascular Endothelial Growth Factor Albuminuria Diabetes Mellitus Genetic Polymorphism
2015/10/20
Background: Angiotensin-converting enzyme (ACE) insertion/deletion (I/D) and vascular endothelial growth factor (VEGF) polymorphisms have been shown to associate with diabetic nephropathy (DN).
A Study on Proteolytic Enzyme Activity in the Erythrocytes of Diabetic Patients
Oxidative stress Proteolytic activity Diabetes mellitus
2015/7/21
The present study demonstrates the possibility of increased proteolytic activities in diabetic individuals. Proteolytic activity was measured by the amount of amino group released by the erythrocyte l...
Viral Hepatitis And Enzyme Study
Jaundice enzyme assay correlation hepatocellular damage cholestasis
2015/7/21
The present study was undertaken in sixty patients of viral hepatitis of both sexes ranging 20 to 60 yrs. of age to compare serum levels or 5’Nucleotidase, Alkaline phosphatase, aspartate aminotransfe...
Cholecystitis & An Enzyme Study
Liver function enzyme markers clinical evaluation gall bladder.
2015/7/14
Cholecystitis is inflammation of the gallbladder that develops in short time usually when gallstone obstructs the cystic duct. Patients over the passage of time land to chronic cholecystitis. They hav...
Association of Cardiorespiratory Fitness with Elevated Hepatic Enzyme and Liver Fat in Japanese Patients with Impaired Glucose Tolerance and Type 2 Diabetes Mellitus
Cardiorespiratory fitness hepatic enzyme non-alcoholic fatty liver abdominal obesity insulin resistance
2015/5/5
No study has so far determined whether a favorable level of cardiorespiratory fitness (CF) contributes to a reduced risk of elevated hepatic enzymes and a high degree of liver fat in patients having v...
Enhanced mtDNA repair and cellular survival following oxidative stress by targeting the hOGG repair enzyme to mitochondria
DNA repair DNA damage
2014/12/12
Oxidative damage to mtDNA has been implicated as a causative factor in many disease processes and in aging. We have recently discovered that different cell types vary in their capacity to repair this ...
Conditional Targeting of the DNA Repair Enzyme hOGG1 into Mitochondria
DNA repair mitochondria
2014/12/12
Oxidative damage to mitochondrial DNA (mtDNA) has been suggested to be a key factor in the etiologies of many diseases and in the normal process of aging. Although the presence of a repair system to r...
APE1/Ref-1 (APE1), the mammalian ortholog of Escherichia coli Xth, and a multifunctional protein possessing both DNA repair and transcriptional regulatory activities, has a pleiotropic role in control...
FcγR-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome
NADPH oxidase p40phox
2014/12/12
The phagocyte NADPH oxidase generates superoxide for microbial killing, and includes a membrane-bound flavocytochrome b558 and cytosolic p67phox, p47phox, and p40phox subunits that undergo membrane tr...
Matrix Metalloproteinase-9 (MMP9)—A Mediating Enzyme in Cardiovascular Disease, Cancer, and Neuropsychiatric Disorders
Cardiovascular Disease Neuropsychiatric
2009/9/3
Matrix metalloproteinase-9 (MMP9) has been implicated in numerous somatic illnesses, including cardiovascular disorders and cancer. Recently, MMP9 has been shown to be increasingly important in severa...
The Effect of Caffeic Acid Phenethyl Ester (CAPE) Treatment on Levels of MDA,NO and Antioxidant Enzyme Activities in Retinas of Streptozotocin-Induced Diabetic Rats
Antioxidant enzymes caffeic acid phenethyl ester diabetic retinopathy lipid peroxidation
2009/6/16
Aim: This study was performed to determine the effect of caffeic acid phenethyl ester (CAPE) treatment on levels of malondialdehyde (MDA) and nitric oxide (NO) and activities of antioxidant enzymes in...
Enzyme-Linked Immunosorbent Assays with High Sensitivity for Antigen-Specific and Total Murine IgE: A Useful Tool for the Study of Allergies in Mouse Models
allergen-specific IgE blocking reagent enzyme-linked immunosorbent assay
2010/11/16
Enhancer solutions are effective in improving ELISAs for total and antigen-specific murine IgE. Selection of blocking reagents was important to decrease unwanted enhancement of background signals and ...
Association of Angiotensin Converting Enzyme (ACE) Gene Polymorphism and Diabetic Nephropathy
Angiotensin converting enzyme Genetic polymorphism Insertion/deletion Diabetic nephropathy Iran
2010/2/1
Angiotensin I-converting Enzyme (ACE) gene polymorphism; genotype DD or D allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (DN). We examined the freq...
EFFECTS OF CIGARETTE SMOKING ON ERYTHROCYTE ANTIOXIDATIVE ENZYME ACTIVITIES AND PLASMA CONCENTRATIONS OF THEIR COFACTORS
Tobacco selenium zinc copper iron antioxidative enzymes
2010/2/4
Tobacco smoke contains numerous compounds, many of which are oxidants and capable of producing free radical and enhancing the oxidative stress. The aim of this study was to investigate t...