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The role of SWI/SNF in regulating smooth muscle differentiation
Brm smooth muscle knockout
2015/5/22
There are many clinical diseases involving abnormal differentiation of smooth muscle, such as atherosclerosis, hypertension and asthma. In these diseases, one important pathological process is the dis...
High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/12/4
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Comparison of Proliferation,Senescence and Differentiation into Skeletal Cell Lineages of Murine Bone Marrow-Derived and Amniotic Fluid Mesenchymal Stem Cells
Amniotic fluid Bone marrow Mesenchymal stem cells Proliferation Differentiation
2015/9/21
Background: While mesenchymal stem cells (MSCs) have been isolated from multiple tissue sources, the differences existed between the cells from different tissues have still remained to be clarified. T...
Dendritic Cells—A Conductor of T Cell Differentiation—
dendritic cells regulatory T cells Th1 Th2 Th17
2010/11/18
Induction of different types of adaptive immune responses depending on the nature of antigens and the environmental context is crucial to cope with a variety of pathogens and concurrently to avoid pat...
Differentiation of naive human CD4+ T cells into Th2 cells: The role of prostaglandin E2
interleukin naive CD4+ T cells prostaglandin E2 T-helper 2 cells
2010/11/26
T-helper (Th) 2 cells, which produce interleukin (IL)-4, IL-5, IL-10 and IL-13 upon stimulation of their T cell receptors, play an important role in the development of human allergic diseases. However...