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Basophils and mast cells are major players in the progression of allergic disorders. Although both cell types originate from hematopoietic stem cells, their lineage commitment pathways and mechanisms ...
Applying Surface Plasmon Resonance to Monitor the IgE-Mediated Activation of Human Basophils
basophil biosensor histamine release IgE surface plasmon resonance
2010/11/17
When basophils were sensitized with antigen specific IgE, they immediately caused the increase of resonance angle (AR) in response to either anti-IgE antibody or corresponding antigens, even when they...
Roles of IL-18 in Basophils and Mast Cells
basophils IL-18 mast cells nematode infection Th2 cytokines
2010/11/18
Basophils and mast cells are effecter cells in allergen/IgE-mediated immune responses. They induce type 1 immediate immune response in airway or other organ, resulting in bronchial asthma and other al...
Basophils: A Potential Liaison between Innate and Adaptive Immunity
adaptive immunity basophils IL-4 innate immunity parasites
2010/11/18
Activation of innate immunity is closely associated to development of protective adaptive immune response. Significant advances have been made to reveal such links between innate immunity and Th1 type...