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Immunomodulatory role of leptin treatment in experimental sepsis caused by gram negative bacteria
Cytokines leptin myeloperoxidase rat sepsis
2011/3/22
To investigate the effect of leptin treatment on circulating inflammatory cytokines and on tissue damage in experimental rat model of gram-negative sepsis. Materials and methods: Adult male Wistar rat...
In addition to its role in regulating feeding behavior and energy homeostasis, leptin, an adipokine (adipose tissue-secreted cytokine) (1,2), may also control lymphocyte and macrophage functions (3). ...