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Scientists have successfully regenerated cells in the retina of adult mice at the University of Washington School of Medicine in Seattle.Their results raise the hope that someday it may be possible to...
RNA Synthesis in the Tracheal Epithelial Cells of Aging Mice as Revealed by Electron Microscopic Radioautography
RNA synthesis Macromolecular Microscopic radioautography 3H-uridine
2015/7/21
For the purpose of studying the aging changes of macromolecular synthesis in the tracheal epithelial cells of experimental animals, we studied 10 groups of aging mice during development and aging from...
Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
STAT6VT transgenic Atopic Dermatitis
2015/5/25
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the dis...
Nf1-DEFICIENT MICE DISPLAY SOCIAL LEARNING DEFICITS THAT ARE RESCUED BY THE DELETION OF PAK1 GENE
Neurofibromatosis type 1 (NF1) social learning p21-activated kinase 1 (PAK1) MAPK prefrontal cortex basolateral amygdala
2015/5/21
Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder that affects roughly 1 in 3500 individuals. In addition to physical features (e.g., neurofibromas), developmental disorders are also common ...
Lithium effects on ethanol intake in impulsive mice
lithium ethanol mice intakes pharmacological manipulation
2015/1/9
The present study sought to identify the effects of chronic lithium administration on ethanol intakes in high alcohol-preferring (HAP) mice. Lithium is a well-established treatment for bipolar disorde...
Intravenous Self-Administration of Alcohol in Selectively Bred High- and Low- Alcohol Preferring Mice
Genetic vulnerability alcoholism gene alcohol dependence animal model genetic vulnerability
2015/1/9
Genetic vulnerability to alcoholism is theorized to be caused by multiple interacting genetic loci, each with a small to modest effect combining under certain environmental influences to contribute to...
Exercise-Induced Changes in the Cortical Bone of Growing Mice Are Bone and Gender Specific
mechanical properties pQCT matrix changes
2014/12/4
Fracture risk and mechanical competence of bone are functions of bone mass and tissue quality, which in turn are dependent on the bone's mechanical environment. Male mice have a greater response to no...
High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/12/4
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Of mice, not men（图）
mice Brain function medical
2014/12/1
For more than a century, the laboratory mouse (Mus musculus) has stood in for humans in experiments ranging from deciphering disease and brain function to explaining social behaviors and the nature of...
Engraftment of bone marrow-derived cells after nonlethal radiation in syngeneic C57BL/6 mice
Chimerism Bone marrow-derived cells Nonlethal radiation
2015/11/24
To study the characteristics of cell engraftment in mice at a lower dose under nonlethal radiated condition.Methods A syngeneic C57BL/6 mouse model, transplanted with 1×107 bone marrow cells and expos...
Fibronectin Regulation by Vitamin C Treatment in Kidneys of Nicotinic Mice Offspring
Vitamin C Nicotine Fibronectin Kidney
2015/10/13
Background: Maternal cigarette smoking causes health risks and developmental defects in the offspring. So far, many studies have been conducted to suppress the effects of nicotine. However, the effect...
Melatonin and Testicular Damage in Busulfan Treated Mice
Melatonin Spermatogenesis Busulfan Mice Testis
2015/10/10
Background:: Advancement in the treatment of various types of cancer has led to greater patient survival. These treatments essentially have toxic effects on different kinds of cells, such as germ cell...
Scientists from USC and NYU design a molecule that blocks cancer growth in mice
Scientists from USC NYU design a molecule blocks cancer growth in mice
2014/6/12
A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.
The molecule prevents two critical proteins from ...
Mice give ticks a free lunch-Amplifying Risk of Lyme Disease and Other Tick-Borne Ailments
Mice free lunch Risk of Lyme Disease Other Tick-Borne Ailments
2014/3/28
(Millbrook, NY) People living in northern and central parts of the U.S. are more likely to contract Lyme disease and other tick-borne ailments when white-footed mice are abundant. Mice are effective a...
Toxoplasmosis:Experimental Vaginal Infection in NMRI Mice and Its Effect on Uterin, Placenta and Fetus Tissues
Infection Toxoplasma Vaginal NMRI Mice
2015/10/8
Background: Toxoplasma gondii is an important zoonotic pathogen. Vertical transmission of the parasite occurs when females were infected primarily during gestation. This parasite is transmitted to the...