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MOLECULAR MODELLING OF HUMAN ALDEHYDE OXIDASE AND IDENTIFICATION OF THE KEY INTERACTIONS IN THE ENZYME-SUBSTRATE COMPLEX
Aldehyde oxidase Molecular modeling 3D-QSAR genetic algorithm
2009/12/25
Aldehyde oxidase (EC 1.2.3.1), a cytosolic enzyme containing FAD, molybdenum and iron-sulphur cluster, is a member of non-cytochrome P-450 enzymes called molybdenum hydroxylases which is involved in t...
The purpose of this study was to detect the physiological process of FDG's filtration from blood to urine and to establish a mathematical model to describe the process. Dynamic positron emission tomog...
The problems in the modelling of inert gas kinetics
DIVING MODELS inert gas kinetic DECOMPRESSION Bubble ELIMINATION
2009/5/26
The models used to describe the kinetics of inert
gases during underwater diving are inadequate. Medical
practitioners and scientists interested in such diving have
attempted to quantitatively desc...
The development of the baboon prostate:ultrasound methodology, modelling, and natural history
Prostate Papio hamadryas ultrasound planimetry
2009/2/16
In order to evaluate the potential of ultrasound for serial, nontraumatic estimation of prostate size in the hamadryas baboon (Papio hamadryas), we adapted the technique of planimetric ultrasound...
Medical imaging and physiological modelling: linking physics and biology
Medical imaging physiological modelling physics and biology
2010/2/25
Medical image analysis is increasingly providing a sophisticated set of tools for processing measurement inputs into clinically relevant outputs, although this is, on the whole, completed without cons...
A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms
modelling techniques wall stress abdominal aortic aneurysms
2010/2/25
The results here show that using more realistic parameters affect resulting wall stress. The use of simplified computational modelling methods can lead to inaccurate stress distributions. Care should ...
Review of "Stochastic Modelling for Systems Biology" by Darren Wilkinson
Stochastic Modelling Systems Biology Darren Wilkinson
2010/2/26
"Stochastic Modelling for Systems Biology" by Darren Wilkinson introduces the peculiarities of stochastic modelling in biology. This book is particularly suited to as a textbook or for self-study, and...
Utilizing FEM-Software to quantify pre- and post-interventional cardiac reconstruction data based on modelling data sets from surgical ventricular repair therapy (SVRT) and cardiac resynchronisation therapy (CRT)
FEM-Software cardiac reconstruction data surgical ventricular repair therapy cardiac resynchronisation therapy
2010/2/26
The operation results for both patients are quantified. The quantification shows treatment details for both interventions (e.g. the elimination of the discontinuities for CRT intervention and the segm...