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Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma
arachidonic acid Calotropis gigantea ovalbumin
2015/7/21
The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxyge...
Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production
vitamin C cyclooxygenase-2 oxidative stress Alzheimer’s disease stroke reactive oxygen species neuroinflammation NSAIDs 8-isoprostanes prostaglandin E synthase
2015/8/3
Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to protect neuronal cells in a variety of pathop...
Inhibitory effect of farnesol on biofilm formation by Candida tropicalis
Farnesol Biofilm Candida tropicalis Azole
2009/12/16
Background: Candidiasis associated with indwelling medical devices is especially problematic since they can act as substrates for biofilm growth which are highly resistant to antifungal drugs. Farneso...
Inhibitory synpatic transmission in striatal neurons after transient cerebral ischemia
large aspiny neurons transient cerebral ischemia striatum
2015/5/21
In the striatum, large aspiny (LA) interneurons survive transient cerebral ischemia while medium spiny (MS) neurons die. Excitotoxicity is believed to be the major cause for neuronal death after ische...
Free radical reactions and the inhibitory and lethal actions of high-pressure gases
superoxide dismutase Free radical paraquat methyl viologen Escherichia coli
2009/7/14
This study was designed to test whether free radicals are involved in the deleterious effects of compressed gases on cells. The actions of xenon, nitrous oxide, argon, nitrogen, helium, and oxygen and...
The Inhibitory Effect of Zinc on Imipenem and Meropenem Susceptibility of Pseudomonas aeruginosa
P.aeruginosa Zinc Imipenem Meropenem
2009/7/2
In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) medi...
Comparison of Inhibitory and Bactericidal Activities of Cefoperazone + Sulbactam Against Pseudomonas aeruginosa Strains,from 1992 to 1994
Pseudomonas aeruginosa cefoperazone+sulbactam MIC MBC susceptibility determination
2009/6/30
In this study; inhibitory and bactericidal activities of cefoperazone + sulbactam against Pseudomonas aeruginosa strains were determined in two studies first in 1992 and second in 1994. Minimum inhibi...
Nitric oxide amplifies the excitatory to inhibitory neurotransmitter imbalance accelerating oxygen seizures
Oxygen Toxicity central nervous system convulsion Seizures/chemically induced seizure nitric oxide HYPERBARIC CONDITIONS Animal Rat aspartate glutamate gamma-aminobutyric acid excitotoxicity index
2009/6/2
CNS O2 toxicity is manifested most profoundly by generalized motor convulsions. The hypothesis was tested that HBO2 triggers seizures by an excitatory to inhibitory neurotransmitter imbalance produced...
Excitatory and inhibitory amino-acidergic determinants of the pressure - induced neuronal hyperexcitability in rat hippocampal slices
rat animal hippocampal slices
2009/3/28
In a previous study we found that the intrinsic excitability of the hippocampal CA1 pyramidal cells increased under helium pressure (80 bar). We presently show that drugs inhibiting gamma-aminobutyric...
Inhibitory Effect of Oxovanadium（IV）, Copper（II）, and Zinc（II）Ions on the Activity of an Alpha-glucosidase from a Saccharomyces sp.
Alpha-glucosidase inhibition Anti-diabetic effect STZ-mice Oral carbohydrate tolerance test Metal ions
2009/3/23
We investigated the in vitro and in vivo effects of metal ions on the activity of an alpha-glucosidase (Saccharomyces sp.). CuSO4, ZnSO4, and VOSO4 significantly inhibited the alpha-glucosidase activi...
Inhibitory Modulation of Glutamatergic Neuron Activity by Zinc in the Hippocampus
zinc glutamate mossy fiber hippocampus calcium exocytosis synaptic plasticity
2009/3/23
Zinc exists in high densities in the giant boutons of hippocampal mossy fibers. Zinc decreases extracellular glutamate concentration in the hippocampus, suggesting inhibitory modulation of glutamaterg...
Inhibitory effect of the nucleus reticularis pontis oralis on the pontine micturition center and pontine urine storage center in decerebrate cats
nucleus reticularis pontis oralis pontine micturition center pontine urine storage center decerebrate cats
2009/3/2
The influence of the nucleus reticularis pontis oralis (PoO) on the pontine micturition center (PMC) and pontine urine storage center (PUSC) was examined in decerebrate cats by electrical and chemic...
Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages
eugenol compounds nitric oxide RAW264.7 macrophages
2009/3/2
Effects of eugenol compounds on the production of nitric oxide (NO) in RAW264.7 macrophages were analyzed in relation to the anti-inflammatory action of these compounds. Eugenol and isoeugenol inhib...
Bladder volume-dependent excitatory and inhibitory influence of lumbosacral dorsal and ventral roots on bladder activity in rats
Bladder volume-dependent excitatory inhibitory lumbosacral dorsal ventral roots bladder activity
2009/3/2
This study was undertaken to examine the role of the afferent and efferent pathways of the lumbosacral spinal nerve roots in the tonic control of bladder activity. Changes of isovolumetric bladder a...
Further Studies on the Inhibitory Effect of [D-A1a6, des-Gly-NH210]LHRH Ethylamide on Spermatogenesis and Steroidogenesis in the Rat：Reversibility and Effect of Androgen Administration
antifertility spermatogenesis LHRH agonist
2009/2/18
Following the recent observation that chronic treatment with [D-Ala6, des-Gly-NH210]LHRH ethylamide, a potent LHRH agonist, leads to an almost complete degeneration of seminiferous tubules in the ra...