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Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
2019-nCoV SARS-CoV ACE2 monoclonal antibody RBD
2020/6/12
The newly identified 2019 novel coronavirus (2019-nCoV) has caused more than 11,900 laboratory-confirmed human infections, including 259 deaths, posing a serious threat to human health. Currently, how...
Monoclonal antibody treatment to prolong the secondary cardiac allograft survival in alloantigen-primed mice
Monoclonal antibody mice
2013/6/26
We have previously shown that costimulation blockade using a combination of monoclonal antibodies (mAbs) - CTLA4Ig, antibodies to CD154, LFA-1, and OX40L - can induce tolerance of cardiac allografts i...
Evaluation of tumor targeting with radiolabeled F(ab)2 fragment of a humanized monoclonal antibody
Humanized monoclonal antibody F(ab)2 fragment I-125
2010/1/6
Humanized monoclonal antibody U36 and its F(ab')2 fragment, radio labeled with 125I, were tested for tumor localization in nude mice bearing a squamous cell carcinoma xenograft line derived from a hea...
Autosomal Recessive Chronic Granulomatous Disease,IgA Deficiency and Refractory Autoimmune Thrombocytopenia Responding to Anti-CD20 Monoclonal Antibody
Anti-CD20 Autoimmune thrombocytopenia Chronic granulomatous disease IgA deficiency Primary immunodeficiency diseases
2009/12/17
Immunodeficiency and autoimmune disease may occur concomitantly in the same individual. Some of the immunodeficiency syndromes, especially humoral defects are associated with autoimmune disorders. Hem...
《Current Trends in Monoclonal Antibody Development and Manufacturing》(图)
Current Trends in Monoclonal Antibody Development and Manufacturing Steven J. Shire Wayne Gombotz Karoline Bechtold-Peters James Andya
2013/12/4
Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years...
Production of Monoclonal Antibody Specific for Human Hemoglobin
Institue for Genetic Engineering and Biotechnology,TÜ Bİ TAK Marmara Research Center,Gebze,Kocaeli Department of Medical Biology,Faculty of Medicine,Marmara University,İ stanbul-TURKEY
2009/6/29
Hemoglobin is not normally present in sputum, urine or feces except in minute amounts. Demonstration of the presence of hemoglobin in these materials is an important diagnostic clue that usually impli...
Measurement of Urine Albumin Levels With A Monoclonal Antibody Based in-House Elisa
Human albumin Monoclonal antibody Polyclonal antibody ELISA
2009/6/25
Microalbuminuria is considered to be an early indicator of diabetic nephropathy. We have previously reported the establishment of A-HAlb/98 hybridoma secreting monoclonal antibody that specifically re...
Molecular characterizations of an intraacrosomal antigen defined by HS-33 monoclonal antibody
Sperm antigen anti-sperm antibodies acrosome reaction
2009/2/17
Among the numerous anti-sperm monoclonal antibodies generated in our laboratory, HS-33 was shown to react with a conserved antigen on the acrosome of spermatozoa from human and mouse. By using ind...
Stage-specific expression of a protein of the acrosome of baboon sperm during spermiogenesis detected with a monoclonal antibody
Spermatogenesis spermiogenesis acrosome monoclonal antibody
2009/2/7
A single monoclonal antibody, BSA4, raised against baboon epididymal sperm was used to study the ontogeny of the baboon sperm acrosome region during testicular spermiogenesis. This antibody is not s...
Monoclonal Antibody From Vasectomized Mouse Identifies a Conserved Testis-Specific Antigen TSA70
Vasectomy testicular auto antigen acrosomal matrix capacitation
2008/12/23
Vasectomy results in the occlusion of testicular outflow, leading to autoimmunity characterized by the production of antisperm antibodies (ASA). Reports on the rise in ASA following vasectomy in sev...
Identification and Characterization of an Antigen Recognized by Monoclonal Antibody TRA 54 in Mouse Epididymis and Vas Deferens
Testis sperm antigens cryptorchidism castration testosterone replacement
2008/12/22
Spermatozoa in testicular fluid are known to have weak forward motility and cannot fertilize eggs. The epididymis is known to participate in sperm maturation leading fertilization, but little is k...
Identification and Characterization of an Antigen Recognized by Monoclonal Antibody TRA 54 in Mouse Epididymis and Vas Deferens
Testis sperm antigens cryptorchidism castration testosterone replacement
2008/12/22
Spermatozoa in testicular fluid are known to have weak forward motility and cannot fertilize eggs. The epididymis is known to participate in sperm maturation leading fertilization, but little is k...
Identification and Characterization of an Antigen Recognized by Monoclonal Antibody TRA 54 in Mouse Epididymis and Vas Deferens
Testis sperm antigens cryptorchidism castration testosterone replacement
2008/12/22
Spermatozoa in testicular fluid are known to have weak forward motility and cannot fertilize eggs. The epididymis is known to participate in sperm maturation leading fertilization, but little is k...
Application of Radioimmunoassay Technique for Determination of Antigen Concentration in Different Cells with a New Monoclonal Antibody
PET/CT X-ray CT Attenuation correction CTAC Hybrid imaging Contrast medium Artifact
2010/2/8
Introduction: Binding a monoclonal antibody to tumor associated antigens is an effective method for cancer therapy because these agents can specifically target malignant cells, in fact monoclonal anti...
A new monoclonal antibody radiopharmaceutical for radioimmunoscintigraphy of breast cancer: direct labeling of antibody and its quality control
Breast cancer MUC1 Monoclonal antibody Technetium-99m-radiolabeling
2010/2/3
Radioimmunoscintigraphy (RIS) has found widespread clinical application in tumor diagnosis. The antibody (Ab) PR81 is a new murine anti-MUC1 monoclonal antibody (MAb) against human breast carcinoma. I...