搜索结果: 1-4 共查到“医学 HYNIC”相关记录4条 . 查询时间(0.046 秒)
99mTc-HYNIC-annexinⅤ活体检测单次放疗后肿瘤细胞凋亡
膜联蛋白Ⅴ 肿瘤 细胞凋亡 放射治疗
2014/5/16
本研究旨在采用99mTc-HYNIC-annexinⅤ活体检测放疗后肿瘤的凋亡情况，并初步探讨凋亡与照射剂量及肿瘤敏感性的关系。方法：将EL4 淋巴瘤和S180 肉瘤细胞株分别接种于实验小鼠右腋下10d，随机分成显像组和观察组。显像组不同剂量照射后尾静脉注射99mTc-HYNIC-annexinⅤ，2 h 后SPECT 显像，取组织称重后分别测量放射性计数，计算每克组织百分注射剂量率（%ID/g）...
一种潜在5-HT1A脑受体显像剂99Tcm-Bicine/HYNIC-MPP2的制备及其生物性能
5-HT1A受体 99Tcm 2-(4-(2-甲氧基苯基)哌嗪基)乙胺-6-叔丁基氧羰基肼基吡啶-3-甲酸（HYNIC-MPP2) 生物分布
2009/12/24
优化合成了含有1-(2-甲氧基苯基)哌嗪(MPP)结构的配体2-(4-(2-甲氧基苯基)哌嗪基)乙胺-6-叔丁基氧羰基肼基吡啶-3-甲酸(HYNIC-MPP2)。在室温下以N,N-二(2-羟基乙基)氨基乙酸(Bicine)为共配体制备得到配合物99Tcm-Bicine/HYNIC-MPP2，其放射化学纯度大于95%，并且在6 h内保持稳定。脂水分配系数和电泳实验结果表明，该放射性标记配合物是水溶性...
New Peptide Based Freeze-Dried Kit [99mTc-HYNIC]-UBI 29-41 as a Human Specific Infection Imaging Agent
Antimicrobial peptide HYNIC Kit Ubiquicidin
2009/12/16
Introduction: Ubiquicidin 29-41 (UBI) is a fragment of the cationic antimicrobial peptide that is present in various species including humans. The purpose of this study was to investigate radiochemica...
Synthesis, development and preclinical comparison of two new peptide based freeze-dried kit formulation 99mTc-EDDA-Tricine-HYNIC-TOC and 99mTc-EDDA-Tricine-HYNIC-TATE for somatostatin receptor positive tumor scintigraphy
99mTc Somatostatin Tyr3-octreotide Tyr3-Octreotate HYNIC Kit formulation
2010/4/7
Somatostatin receptor (sstr) scintigraphy with [111In diethylenetriaminepentaacetic acid]-octreotide ([111In-DTPA]-OC) has became a routine diagnostic procedure in oncology. However, it suffers from s...