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真菌性角膜炎是一种由致病真菌引起的致盲率极高的眼部感染性疾病。若感染早期未及时诊断和治疗,炎症则会迅速进展,引起角膜混浊、溃疡、穿孔,不仅会导致严重的眼内炎,还会导致颅内感染扩散。那他霉素是唯一一个被美国食品药品监督管理局批准用于控制真菌性角膜炎的滴眼液,具有抗菌谱广、抗菌能力强、不良反应少等优点。但是那他霉素难溶于水,目前市面上只有5%的那他霉素悬浊液(那特真)存在。那特真价格昂贵,除此之外,由...
Chemists at the University of Alabama at Birmingham have designed triple-threat cancer-fighting polymer capsules that bring the promise of guided drug delivery closer to preclinical testing....
Pharmaceutical reseaches aim at mechanistically uncovering the pharmacokinetic profiles of drugs, and at developing techniques of controlling and manupilating them into desirable appearances. With tim...
A team of University of Pennsylvania researchers has developed a computer model that will aid in the design of nanocarriers, microscopic structures used to guide drugs to their targets in the body. Th...
Vesicular systems have been realized as extremely useful carrier systems in various scientific domains. Sphingosomes is bilayered vesicles in which an aqueous volume is entirely enclosed by membrane l...
This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug deliv...
Stimuli-sensitive polymers are suitable candidates for novel drug delivery systems, since they release drugs in a controlled manner in response to a stimulus such as temperature. In the present study ...
0 Microfabrication technology, more commonly applied to the manufacture of integrated circuits, can be used to build devices useful for mechanical delivery of drugs and genes. Microprobes fabricat...
This study sought to clarify the effectiveness of bFGF-gelatin hydrogel complex on bone regeneration around implants for the development of a new drug delivery system for bone augmentation. Twenty-fou...
This paper describes the development of microcapsules with high disintegration rate efficiency for drug delivery systems (DDS) using shock waves and the design of the microcapsules. The microcapsules,...
Combined Cancer Therapy of Ultrasound and Drug Delivery.
We investigated the setting and modification of programs for intelligent drug delivery using an infrared communication method. We connected a hydrogel or motor-driven type device to a sensor and a cli...
The reader is introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptid...
The floating microspheres have been utilized to obtain prolonged and uniform release in the stomach for development of a once daily formulation. The major advantage of the preparation technique includ...

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