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Safety assessment of sanguiritrin, alkaloid fraction of Macleaya cordata, in rats
benzo[c]phenanthridine alkaloids oral administration biochemical markers oxidative stress DNA damage cytochrome P450
2015/3/5
The subchronic safety of sanguiritrin, a mixture of sanguinarine (SA) and chelerythrine (CHE) quaternary benzo[c]phenanthridine alkaloids (QBA), obtained from Macleaya cordata was assessed. Rats were ...
Alkaloid diversity in relation to breeding for specifi c alkaloids in opium poppy (Papaver somniferum L.)
alkaloids clustering multivariate Papaver somniferum
2014/3/10
Papaver somniferum is a chief source of diverse physiologically active alkaloids, required by the pharmaceutical industry. The present study describes the diversity of the alkaloid spectrum of 122 opi...