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Synergistic Effect of Dexamethasone and Prolactin on VEGF Expression in Bovine Mammary Epithelial Cells via p44/p42 MAP Kinase
p44/p42 MAP Kinase Prolactin Dexamethasone VEGF Bovine Mammary Epithelial Cells
2016/4/29
Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis under various physiological and pathological conditions. We found that the VEGF isoforms VEGF120, VEGF164, and VEGF188 were...
妊娠合并糖尿病诱发胚胎先天性神经管缺陷动物模型的MAP 激酶信号传导机制MAP Kinase Signal Pathway in Hyperglycemia-induced Congenital Neural tube defects
神经管缺陷 糖尿病 激酶 ERK JNK/SAPK RAF-1 动物模型
2008/1/20
摘要
为了揭示妊娠合并糖尿病诱发胚胎先天性神经管缺陷的分子机制，并探讨其有效的防治方法。 实验选用6个实验组的 Sprague-Dawley 大鼠：第1组为常规饲养的正常对照组；第2组尾静脉注射65mg/kg Streptozotocin (STZ) 构建妊娠合并糖尿病、且诱发先天性神经管缺陷的实验组大鼠；第3组为STZ构建的糖尿病、但胚胎不伴有先天性神经管缺陷的大鼠模型；第4、5、6 组为 S...
MAP Kinase is Activated dring the Maturation of Porcine Oocytes
Porcine Oocytes Maturation Western Blotting MAP Kinase Phosphorylation
2016/4/15
In an attempt to evaluate the function of MAP kinase in porcine oocytes and to develop a method of the assessment of its activity, myelin basic protein (MBP) was used as a substrate to detect the MAP ...